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NASA Astronaut Chris Williams Closes Out Space Station Mission

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NASA Astronaut Chris Williams Closes Out Space Station Mission

After eight months aboard the International Space Station for his first mission, NASA astronaut Chris Williams is preparing to return to Earth. During his assignment, Williams contributed to research for new cancer treatments, advanced the production of materials to improve computers and electronics, ventured into the vacuum of space to complete two spacewalks, and much more. Williams’ work aboard the space station helped to improve life on Earth and prepare for future missions to the Moon and Mars.

Here are some of the research highlights from his mission:

Cancer-fighting constructs

NASA astronaut Chris Williams and ESA (European Space Agency) astronaut Sophie Adenot work together at the International Space Station's Life Sciences Glovebox. Sophie reaches into the illuminated glovebox while Chris floats beside her, smiling toward the camera. Blue cables, scientific equipment, and white station walls surround the workstation.
NASA

NASA astronaut Chris Williams and ESA (European Space Agency) astronaut Sophie Adenot work to process DNA-inspired materials that could advance new cancer treatments for people on Earth. In space, these rod-shaped materials form more evenly and consistently, which may improve their performance and readiness for treatments on Earth. While there have been major advancements in cancer therapies, many treatments can affect the whole body and cause side effects without fully treating solid tumors. This research aims to enable targeted cancer therapies that reach deep into tumors, stay in the body longer, and release medicine in a more controlled way.

Learn more about DNA Nano Therapeutics-3.

Superior semiconductors

NASA astronaut Chris Williams smiles while reaching into the Microgravity Science Glovebox. The inside of the rectangular workspace is illuminated by white light. There is a plastic bag floating inside the upper left side of the glovebox, and Chris holds a small black and silver object in his hands.
NASA

NASA astronaut Chris Williams conducts research to grow semiconductor crystals in space. In microgravity, researchers can grow more crystals of the desired size than can be produced on Earth. Previous research shows that space-grown crystals can offer increased performance to help advance technologies like high-performance computers, artificial intelligence, and medical devices. This research lays the groundwork for commercial semiconductor manufacturing in space and advances the semiconductor industry.

Learn more about In-Space Production of Semimetal-Semiconductor Composite Bulk Crystals in Microgravity (SUBSA-InSPA-SSCug).

Eyeing Earth

NASA astronaut Chris Williams gazes out of a trapezoid-shaped window at a glowing red aurora above the Earth. The curvature of the Earth is visible through a bright green curve. It is dark aboard the International Space Station in the photo, and the glow from the aurora softly illuminates Williams' face.
Roscosmos

NASA astronaut Chris Williams looks out of a cupola window at a red aurora glowing above the Earth. Since the 1960s, astronauts have photographed Earth from space to help scientists monitor the planet’s changing landscapes, natural disasters, and other features over time. Along the way, astronauts also have captured images of celestial objects such as comets, auroras, and the Milky Way.

Sub-zero medical samples

NASA astronaut Chris Williams inserts a cryogenic storage unit into the space station's science freezer. The wedge-shaped unit resembles a slice of pie, and Williams wears thick insulated gloves to protect his hands from the extremely cold temperatures. There are many blue cables beneath him.
NASA

NASA astronaut Chris Williams works with a special freezer aboard the International Space Station that keeps research samples at ultra-cold temperatures until they can return to Earth. Throughout each mission, astronauts collect biological samples like blood and urine to help scientists understand how long-duration spaceflight affects the human body. Observing crew members during their space missions and studying these frozen samples back on Earth helps NASA protect astronaut health during future missions to the Moon, Mars, and beyond.

Learn more about the Minus Eighty-Degree Laboratory Freezer for the International Space Station (MELFI) and Human Research.

Capturing cargo

NASA astronauts Jack Hathaway (left) and Chris Williams (right) look through a circular window in the International Space Station's cupola as Northrop Grumman’s Cygnus XL spacecraft approaches. The spacecraft is a silver cylinder with two hexagonal solar arrays extending from either side of the top end of the cylinder. Behind the spacecraft, white clouds cover the Earth.
NASA

NASA astronauts Jack Hathaway and Chris Williams watch from the cupola windows as Northrop Grumman’s Cygnus XL cargo spacecraft approaches the International Space Station. The two played key roles in the capture of the spacecraft, which delivered approximately 11,000 pounds of supplies, including fresh food, life support equipment, and scientific research as part of NASA’s Northrop Grumman Commercial Resupply Services 24 mission. Cargo missions help keep the space station operating and provide astronauts with the supplies they need to live, work, and conduct research in orbit.

Blocking biofilms

NASA astronaut Chris Williams smiles at the camera as he reaches into the clear, sealed Life Sciences Glovebox and holds a transparent orange package. The illuminated workspace contains plastic bags, scientific equipment, and a pair of scissors.
NASA

NASA astronaut Chris Williams works on an investigation that tests the use of ultraviolet light to help prevent the formation of microbial colonies, called biofilms. Biofilms can clog and contaminate water systems, damage equipment, and pose health risks to astronauts. This research aims to keep surfaces cleaner and safeguard systems during long-duration space missions. Using UV light for sanitation also could reduce the need for chemical disinfectants in space, decreasing the risk of chemical exposure and eliminating difficulties in transporting or storing supplies.

Learn more about Germicidal Ultraviolet Light Biofilm Inhibition (GULBI).

Strengthening solar power

NASA astronaut Chris Williams is seen smiling through his spacesuit helmet outside of the International Space Station. Williams is anchored next to several white structures and surrounded by space station equipment. Behind him there is a SpaceX Dragon spacecraft docked to the space station. Earth's blue curvature and scattered white clouds stretch across the background.
NASA

NASA astronaut Chris Williams ventured outside the International Space Station for two spacewalks during his mission. In June, he helped make repairs to Canadarm2, a robotic arm that captures cargo spacecraft and deploys external research. In March, Williams prepared the orbiting laboratory for new solar arrays to be added to the station in a future spacewalk. Once installed, the final set of International Space Station Roll Out Solar Arrays (IROSA) will complete the full suite of additional solar power, increasing the station’s power generation by about 30% and enhancing support for scientific research and daily operations. The same solar array technology also powered NASA’s Double Asteroid Redirection Test and could support future missions to the Moon and Mars.

Learn more about the space station’s IROSAs.

Microgravity medicine

NASA astronaut Chris Williams holds a small, rectangular hard drive as he works to swap computer components for a protein crystal growth investigation. A tablet is secured to one of his legs, while two plastic bags are attached to the other. Bundles of cables float next to him and a circular hatch is visible in the background.
NASA

NASA astronaut Chris Williams works with hardware to support the development of new cancer and disease treatments by studying the growth of protein crystals for pharmaceuticals. In space, protein crystals form higher-quality structures than they do on Earth, allowing researchers to better understand how to target and treat disease. Here, Williams works with a project that aims to develop a new formula for a cancer treatment that could be taken orally. Growing protein crystals in space paves the way for more commercial companies to create new therapies that could improve patient outcomes on Earth.

Learn more about the Pharmaceutical In-space Laboratory (ADSEP-PIL-10).

Robotic refinement

A video shows NASA astronaut Chris Williams working on hardware inside a rectangular space. Facing away from the camera, Williams makes small adjustments to the experiment, which consists of two white robotic arms. There are many white cables on the inside of the compartment.
NASA

NASA astronaut Chris Williams works with equipment that tests the performance of small robotic arms in space. Some experiments and operations require very precise movements, where tiny errors can significantly impact results. Understanding how microgravity affects delicate robotic operations helps researchers improve designs for future automated systems that can perform operations while astronauts focus on the most critical tasks.

Learn more about the Test facility for lab-aUtomation System in Kibo (TUSK).

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Last Updated
Jul 20, 2026

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